| ASML | Lithography systems and semiconductor manufacturing equipment | Core Dutch equipment champion | Named by Dutch government and sector roadmaps as a central semiconductor equipment company | Source |
| ASM International | Wafer-processing and deposition equipment | Major Dutch-listed equipment company | Named in the national semiconductor equipment roadmap and Semicon Board ecosystem | Source |
| Besi | Assembly and advanced packaging equipment | Major Dutch-listed packaging-equipment company | Named in the national roadmap as a semiconductor manufacturing-equipment participant | Source |
| NXP Semiconductors | Mixed-signal, automotive and embedded chip design | Major Dutch semiconductor company | Named by the Dutch government as a major semiconductor player | Source |
| Nexperia | Discrete, logic and power semiconductors | Large Dutch semiconductor operating base | Named by the Dutch government among semiconductor companies active in the Netherlands | Source |
| Axelera AI | AI accelerator chip design | Dutch AI-chip scaleup | Named as a major industry participant in the Dutch semiconductor ecosystem guide and Semicon Board | Source |
| Nearfield Instruments | Semiconductor metrology and inspection | Dutch scaleup in advanced metrology | Named by government and sector roadmaps as a specialist semiconductor supplier | Source |
| SMART Photonics | Indium-phosphide photonic chip foundry | Dutch photonics manufacturing platform | Named by the Dutch government as a photonic semiconductor company | Source |
| EFFECT Photonics | Integrated photonics and optical communications | Dutch photonics company | Named by the Dutch government in the national photonics ecosystem | Source |
| VDL ETG | Precision modules, mechatronics and manufacturing systems | Strategic Brainport supplier | Named by the Dutch government and semiconductor roadmaps as part of the equipment supply chain | Source |
| Neways | Electronics, control and system-integration supplier | Dutch high-tech systems supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| NTS Group | Precision mechatronics and modules | Dutch high-tech equipment supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| Prodrive Technologies | Electronics, control, power and mechatronic systems | Brainport technology supplier | Included in the semiconductor roadmap across multiple technology domains | Source |
| Demcon | High-tech systems, mechatronics and engineering | Dutch engineering supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| KMWE | Precision manufacturing and mechatronic modules | Brainport precision supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| MI-Partners | Precision motion and mechatronic engineering | Specialist Dutch engineering supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| Salland Engineering | Semiconductor test engineering and test applications | Dutch semiconductor test specialist | Named by government as an innovative internationally active semiconductor supplier | Source |
| SolMates | Thin-film deposition equipment | Dutch semiconductor equipment specialist | Included in the semiconductor roadmap for thin-film and deposition technology | Source |
| Technolution | Embedded electronics, control and software systems | Dutch high-tech engineering supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| Tempress Systems | Thermal processing and wafer-production equipment | Dutch semiconductor equipment supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| Thermo Fisher Scientific Netherlands | Electron microscopy and semiconductor metrology capability | Large Netherlands R&D and systems presence | Included in the Dutch semiconductor roadmap for optics, metrology and related technology domains | Source |
| Trymax Semiconductor Equipment | Plasma, etch and surface-treatment equipment | Dutch semiconductor equipment specialist | Named by government as an innovative internationally active semiconductor supplier | Source |
| ITEC | Semiconductor manufacturing and test technology | Dutch semiconductor equipment and manufacturing-technology business | Included in the semiconductor manufacturing equipment roadmap | Source |
| Sioux Technologies | Software, electronics and mechatronic systems | Brainport engineering supplier | Part of the wider Dutch high-tech and semiconductor supplier ecosystem | Source |
| Reden | Engineering, modelling and simulation | Dutch advanced engineering supplier | Included in the semiconductor manufacturing equipment roadmap | Source |
| Nedinsco | Optical and mechatronic systems | Dutch precision-technology supplier | Included in the semiconductor manufacturing equipment roadmap | Source |